The efficacy of using buccal misoprostol to treat missed abortions has not been studied previously to the investigators' knowledge. In fact a study by Fjerstad et al (2009), found a decrease in infection rate for medical abortion when misoprostol administration was switched from vaginal to buccal route combined with routine administration of doxycycline. Buccal misoprostol is used safely in medical abortion. Buccal misoprostol is a way of administering misoprostol by having the patients insert the tablets of misoprostol between their gum and cheek, letting it dissolve for 30 minutes, then swallowing the remaining remnants. Some studies have shown that some women are not comfortable with vaginal insertion of misoprostol and prefer oral administration. Misoprostol can be administered in multiple ways but has been traditionally inserted vaginally when used for management of missed abortions. There are several ways in which missed abortions are managed, one of which involves administering a medication called misoprostol which causes uterine contractions inducing expulsion of the failed pregnancy. When the failed pregnancy does not pass spontaneously on its own, it is called a missed abortion. Why Should I Register and Submit Results?įirst trimester miscarriages are common.
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